4-Nitro-2-((trimethylsilyl)ethynyl)pyridine CAS 667932-20-9
| CAS No. | 667932-20-9 |
| Molecular Formula | C10H12N2O2Si |
| Molecular Weight | 220.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Nitro-2-((trimethylsilyl)ethynyl)pyridine (CAS 667932-20-9), a certified reference material (molecular formula C10H12N2O2Si, MW 220.30 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H12N2O2Si, 4-Nitro-2-((trimethylsilyl)ethynyl)pyridine contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 220.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O2Si |
| Molecular Weight | 220.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
Related Nitro Standards
- 2-Nitro-5-((trimethylsilyl)ethynyl)pyridine (CAS 936342-51-7)
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Recommended Standards
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- 1-Methyl-α-phenyl-1H-benzimidazole-2-methanamine (CAS 13745-37-4)
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- 6-Aminoquinoline-3-carbonitrile (CAS 13669-67-5)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(pyridin-3-ylmethyl)-1H-pyrrole-2-carboxamide (CAS 338397-65-2)
- 6-Chloro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyrazine (CAS 2375920-13-9)
- 3-(Difluoromethyl)-5-(propylthio)-4h-1,2,4-triazol-4-amine (CAS 886496-00-0)
- Insulin aspart (CAS 116094-23-6)
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