(3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid CAS 668463-35-2
| CAS No. | 668463-35-2 |
| Molecular Formula | C28H25F3N2O4 |
| Molecular Weight | 510.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid (CAS 668463-35-2) is a high-purity analytical reference standard with the molecular formula C28H25F3N2O4 and a molecular weight of 510.50 g/mol.
The molecular framework of (3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid (C28H25F3N2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (3R,4R)-4-[3-(6-Methoxyquinolin-4-yl)-3-oxo-propyl]-1-[3-(2,3,5-trifluoro-phenyl)-prop-2-ynyl]-piperidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H25F3N2O4 |
| Molecular Weight | 510.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Rehmannioside C (CAS 81720-07-2)
- 1,3,5-Tri-p-(tetrazol-5-yl)phenylbenzene (CAS 1006608-03-2)
- 8-p-Coumaroylharpagide (CAS 87686-74-6)
- VP 14637 (CAS 235106-62-4)
- 3-(2-Methoxyphenyl)-3-(4-methoxyphenyl)isobenzofuran-1(3H)-one (CAS 6315-82-8)
- N-(3-Bromophenyl)methanesulfonamide (CAS 83922-51-4)
- Ethyl 4-Oxotetrahydrofuran-3-carboxylate (CAS 89898-51-1)
- N,N-dimethyl-2-(piperidin-4-yl)ethan-1-amine dihydrochloride (CAS 102308-92-9)
- Famotidine EP Impurity B (CAS 89268-62-2)
- 2-Cyclohexylpropan-2-amine (CAS 19072-67-4)
- O,O'-(Butane-1,4-diyl)bis(hydroxylamine) (CAS 66080-74-8)
- [D-Asp5]-Atosiban (CAS CATO-C4X-229343)
- 1-Benzyl-4-methoxy-1h-indole-2-carboxylic acid (CAS 1048660-06-5)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com