[2-(4-Isopropylphenyl)-1,3-thiazol-4-yl]-acetic acid CAS 668477-13-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [2-(4-Isopropylphenyl)-1,3-thiazol-4-yl]-acetic acid.

[2-(4-Isopropylphenyl)-1,3-thiazol-4-yl]-acetic acid (CAS 668477-13-2) is a high-purity analytical reference standard with the molecular formula C14H15NO2S and a molecular weight of 261.34 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, [2-(4-Isopropylphenyl)-1,3-thiazol-4-yl]-acetic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 261.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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