Norethisterone Acetate EP Impurity E CAS 66964-58-7
| CAS No. | 66964-58-7 |
| Molecular Formula | C22H30O4 |
| Molecular Weight | 358.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Norethisterone Acetate EP Impurity E (CAS 66964-58-7) is a certified pharmaceutical impurity reference standard with the molecular formula C22H30O4 and a molecular weight of 358.47 g/mol.
Norethisterone Acetate EP Impurity E (C22H30O4) contains a flavonoid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Norethisterone Acetate EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H30O4 |
| Molecular Weight | 358.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
Related Norethisterone Standards
- Norethisterone Acetate EP Impurity F (CAS 6856-27-5)
- Norethisterone Acetate EP Impurity G (CAS 438244-27-0)
- Norethisterone Acetate (CAS 51-98-9)
- Norethisterone Acetate EP Impurity C (CAS 1175129-26-6)
- Norethisterone Acetate EP Impurity B (CAS 19637-28-6)
- Norethisterone Acetate EP Impurity D (CAS CATO-C4X-171316)
- Norethisterone Acetate EP Impurity H (CAS 2417092-17-0)
- Norethisterone EP Impurity F (CAS 96487-85-3)
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- Sn Standard Solution (CAS 7440-31-5)
- 3-(2-Fluorophenyl)-N-(furan-3-ylmethyl)-N-(thiophen-2-ylmethyl)propanamide (CAS 1797214-33-5)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com