Betamethasone EP Impurity J CAS 18383-24-9
| CAS No. | 18383-24-9 |
| Molecular Formula | C22H30O4 |
| Molecular Weight | 358.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Betamethasone EP Impurity J (CAS 18383-24-9), a pharmacopoeial impurity reference standard (molecular formula C22H30O4, MW 358.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Betamethasone EP Impurity J (C22H30O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 358.47 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H30O4 |
| Molecular Weight | 358.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related Betamethasone Standards
- Betamethasone Impurity 94 (CAS 19784-87-3)
- Betamethasone EP Impurity C (CAS 13504-15-9)
- Betamethasone EP Impurity F (CAS 330157-04-5)
- Betamethasone Impurity 75 (CAS CATO-C4X-143775)
- Betamethasone Impurity 128 (CAS CATO-C4X-1437128)
- Betamethasone Impurity 129 (CAS CATO-C4X-1437129)
- Betamethasone Impurity 50 (CAS 1203841-45-5)
- Betamethasone impurity 73 (CAS 1203841-43-3)
Recommended Standards
- N-Nitroso Dorzolamide-D5 (CAS CATO-C4X-122823)
- Butylhydroxyanisole Impurity 2 (CAS 1911-86-0)
- Amlodipine Impurity 115 (CAS 20236-47-9)
- Norethisterone Acetate EP Impurity E (CAS 66964-58-7)
- Trilostane Impurity 2 (CAS 2301065-59-6)
- Acipimox Impurity 13 (CAS CATO-C4X-186613)
- Allopurinol EP Impurity A (CAS 5334-31-6)
- 2-Bromo-4-cyclopropoxy-6-(trifluoromethyl)pyridine (CAS 1243363-26-9)
- 2-(2-(Difluoromethyl)-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2614261-45-7)
- Morinidazole Impurity 33 HCl (CAS CATO-C4X-219644)
- Tert-butyl (4-cyanobicyclo[2.2.1]Heptan-1-yl)carbamate (CAS 2114128-11-7)
- (2R,3R,4S,5R)-2-(6-Amino-2-(3-nitrophenyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 109875-47-0)
- Prasugrel Impurity 37 (CAS 866761-71-9)
- Palmitoyl Tripeptide -5 · 2 TFA (CAS 623172-56-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com