2-(trifluoromethyl)-1H-pyrrole CAS 67095-60-7
| CAS No. | 67095-60-7 |
| Molecular Formula | C5H8F3N |
| Molecular Weight | 139.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(trifluoromethyl)-1H-pyrrole is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(trifluoromethyl)-1H-pyrrole (CAS 67095-60-7), a certified reference material (molecular formula C5H8F3N, MW 139.12 g/mol) for analytical method development and quality control.
2-(trifluoromethyl)-1H-pyrrole (C5H8F3N) contains fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(trifluoromethyl)-1H-pyrrole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H8F3N |
| Molecular Weight | 139.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related trifluoromethyl Standards
- (R)-2-(Trifluoromethyl)pyrrolidine (CAS 1073556-31-6)
- 2-(Trifluoromethyl)pyrrolidine (CAS 109074-67-1)
- 1-(trifluoromethyl)cyclobutan-1-amine (CAS 1113053-52-3)
- 2-(Trifluoromethyl)cyclobutan-1-amine (CAS 1258640-19-5)
- 3-(Trifluoromethyl)cyclobutan-1-amine (CAS 1258651-99-8)
- (R)-3-(Trifluoromethyl)pyrrolidine (CAS 1260619-30-4)
- 1-(Trifluoromethyl)-N-methylcyclopropylamine (CAS 1301818-80-3)
- (2-(Trifluoromethyl)cyclopropyl)methanamine (CAS 1393576-32-3)
Recommended Standards
- 1-Cyclopropyl-2,2,2-trifluoroethan-1-amine (CAS 705243-06-7)
- 3-(trifluoromethyl)-1H-pyrrole (CAS 71580-26-2)
- 1,2,4-Triazine-3-carbohydrazide (CAS 89033-53-4)
- 3-(Trifluoromethyl)pyrrolidine (CAS 644970-41-2)
- 2-Chloro-N-(2,4-dichlorophenyl)propanamide (CAS 379254-94-1)
- (3-Pyridyl)(3-quinolyl)methanol (CAS 1183608-99-2)
- 6-methoxy-1H-indazole-3-carboxylic acid (CAS 518990-36-8)
- 5-(Pyridin-4-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 127236-01-5)
- 1-[4-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-amine (CAS 1170525-72-0)
- Ethyl 3-hydroxy-5-(trifluoromethyl)picolinate (CAS 1803855-22-2)
- Ethyl 2-(4-(4-Chlorophenyl)-1H-pyrazol-1-yl)acetate (CAS 1199773-60-8)
- (2E)-2-Cyano-N,N-diethyl-3-(4-methoxyphenyl)prop-2-enamide (CAS 23795-68-8)
- 5-(2-Chloro-6-fluorophenyl)-3-(chloromethyl)-1,2,4-oxadiazole (CAS 926206-64-6)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
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