5-(Phenylamino)-1,3,4-thiadiazole-2-sulfonamide CAS 67341-56-4

Purity 97%+In StockPharmaceutical Standards
CAS No.67341-56-4
Molecular FormulaC8H8N4O2S2
Molecular Weight256.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(Phenylamino)-1,3,4-thiadiazole-2-sulfonamide CAS 67341-56-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 256.30 g/mol gives 5-(Phenylamino)-1,3,4-thiadiazole-2-sulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-(Phenylamino)-1,3,4-thiadiazole-2-sulfonamide (CAS 67341-56-4), molecular formula C8H8N4O2S2 and molecular weight 256.30 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 5-(Phenylamino)-1,3,4-thiadiazole-2-sulfonamide (C8H8N4O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 256.30 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H8N4O2S2
Molecular Weight256.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Nitrogen Atoms4
Sulfur Atoms2

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