Miconazole Nitrate EP Impurity C Nitrate CAS 67358-54-7(Free Base)
| CAS No. | 67358-54-7(Free Base) |
| Molecular Formula | C15H13Cl4NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Miconazole Nitrate EP Impurity C Nitrate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Miconazole Nitrate EP Impurity C Nitrate (CAS 67358-54-7(Free Base)), a pharmacopoeial impurity reference standard (molecular formula C15H13Cl4NOHNO3, MW 428.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Miconazole Nitrate EP Impurity C Nitrate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 428.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Miconazole Nitrate EP Impurity C Nitrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H13Cl4NO HNO3 |
| Molecular Weight | 428.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Miconazole Standards
- Miconazole-d5 Nitrate (CAS 1216653-51-8)
- Miconazole EP Impurity H (CAS 181931-30-6)
- Miconazole EP Impurity H (CAS 181931-30-6（free base）)
- Miconazole Impurity H nitarte salt (CAS 203264-09-9)
- Miconazole Nitrate (CAS 228321-87-7)
- Miconazole (CAS 22916-47-8)
- Miconazole EP Impurity D (CAS 24168-96-5)
- Miconazole EP Impurity I (CAS 24169-00-4)
Recommended Standards
- Bilastine Impurity 70 (CAS CATO-C4X-225370)
- Cefditoren Impurity 50 (CAS CATO-C4X-135850)
- Meclofenoxate Impurity 4 (CAS CATO-C4X-24694)
- Z-Val-Trp-OH (CAS 18904-53-5)
- 3-Methyl-5,6,7,8-tetrahydropyrazolo[5,1-b][1,3]oxazepine-2-carboxylic acid (CAS 1823437-29-1)
- 6-Chloro-n-(3-methoxypropyl)nicotinamide (CAS 1094316-70-7)
- 5-methyl-5H-pyrimido[5,4-b]indole-2-carbaldehyde (CAS 1557774-01-2)
- 2-(Difluoromethoxy)-3-mercaptophenylpropanal (CAS 1803889-18-0)
- 3-Azabicyclo[3.2.0]heptan-6-one (CAS 1334377-41-1)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com