Miconazole EP Impurity C CAS 67358-54-7
| CAS No. | 67358-54-7 |
| Molecular Formula | C15H13Cl4NO |
| Molecular Weight | 365.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C15H13Cl4NO, Miconazole EP Impurity C contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 365.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Miconazole EP Impurity C (CAS 67358-54-7), a pharmacopoeial impurity reference standard (molecular formula C15H13Cl4NO, MW 365.08 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H13Cl4NO |
| Molecular Weight | 365.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Miconazole Standards
- Miconazole Impurity 15 (CAS 913837-72-6)
- Miconazole EP Impurity I (CAS 47363-37-1)
- Miconazole EP Impurity H (CAS 181931-30-6)
- Miconazole Impurity N1 (CAS 911805-54-4)
- Miconazole EP Impurity D (CAS 27523-40-6)
- Miconazole EP Impurity F (CAS 47447-55-2)
- Miconazole EP Impurity G (CAS 909277-71-0)
- Miconazole (CAS 22916-47-8)
Recommended Standards
- Isoconazole nitrate EP Impurity B (CAS 1305320-62-0)
- 2-(4-Iodophenoxy)-6-(trifluoromethyl)pyridine (CAS 1227955-16-9)
- 2,4-Dichloro-N-[2-(2,4-dichlorophenoxy)-propyl]aniline (CAS 1040689-46-0)
- 2-(4-Iodophenoxy)-5-(trifluoromethyl)pyridine (CAS 694449-19-9)
- Atosiban Impurity 28 (CAS CATO-C4X-229328)
- Propofol Impurity 52 (CAS CATO-C4X-147352)
- Roxadustat Impurity 75 (CAS CATO-C4X-221375)
- Primapterin (CAS 2582-88-9)
- Valacyclovir Hydrochloride (CAS 124832-27-5)
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- 5-[(2,3-dimethylphenyl)amino]-1,3,4-thiadiazole-2-thiol (CAS 379254-69-0)
- (S)-N-(3-chloro-5-fluorobenzyl)-3-hydroxy-2-oxopyrrolidine-3-carboxamide (CAS 2059084-25-0)
- 2-(4-(2,2,2-Trifluoroethoxy)pyrimidin-2-yl)ethan-1-amine (CAS 944898-83-3)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com