2-Bromo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetamide CAS 67445-86-7
| CAS No. | 67445-86-7 |
| Molecular Formula | C15H11BrClNO3 |
| Molecular Weight | 368.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetamide.
2-Bromo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetamide (CAS 67445-86-7) is a high-purity analytical reference standard with the molecular formula C15H11BrClNO3 and a molecular weight of 368.61 g/mol.
2-Bromo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetamide (C15H11BrClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11BrClNO3 |
| Molecular Weight | 368.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 7-Bromo-5-chloroquinolin-8-yl thiophene-3-carboxylate (CAS 89588-65-8)
- 2-(4-Bromo-2-methylphenoxy)-N-(3-chloro-4-methylphenyl)acetamide (CAS 434303-68-1)
- 2-(4-Bromo-2-methylphenoxy)-N-(4-chloro-2-methylphenyl)acetamide (CAS 434305-75-6)
- N-(3-bromo-4-chlorophenyl)-2-(4-ethylphenoxy)acetamide (CAS 527746-29-8)
- 6-Bromo-2-chloro-5-methyl-8-(spiro[2.4]heptan-4-yl)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 1956332-32-3)
- 6-Bromo-1-chloro-4-iodoisoquinoline (CAS 1254514-20-9)
- 6-Bromo-4-chloro-3-iodoquinoline (CAS 1260787-47-0)
- 8-Bromo-4-chloro-3-iodoquinoline (CAS 1431363-99-3)
Recommended Standards
- (E)-1-((4-bromobenzyl)oxy)-2-chloro-4-(2-nitrovinyl)benzene (CAS 1260890-04-7)
- Bromfenac Impurity 75 (CAS 91715-34-3)
- tert-Butyl 2-(4-chloro-2-iodophenoxy)acetate (CAS 847149-19-3)
- 10-DOXYL-nonadecane, free radical 101829-05-4 4,4-Dimethyl-2,2-dinonyl-3-oxazolidinyloxy, free radical (CAS 101829-05-4)
- Ethyl 2-hydroxy-2-(oxetan-3-yl)acetate (CAS 1509910-39-7)
- 2-Methyl-5-(5-methyl-1h-1,2,4-triazol-3-yl)aniline (CAS 1250032-29-1)
- Primaquine EP Impurity C (CAS 90-52-8)
- 2-hydroxy-4,6-dimethylpyridine-3-carbaldehyde (CAS 937644-31-0)
- ethyl 7-(difluoromethyl)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 938001-08-2)
- 5-Methoxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 6939-11-3)
- tert-Butyl 4-amino-4-(pyridin-3-yl)piperidine-1-carboxylate (CAS 1707580-61-7)
- 2-(1,2-Oxazinan-2-yl)ethan-1-ol (CAS 1357352-12-5)
- 4-Bromo-2-chloro-1H-indole-3-carbaldehyde (CAS 903130-82-5)
- Neuropeptide S (human) (CAS 412938-67-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com