5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole CAS 67445-85-6
| CAS No. | 67445-85-6 |
| Molecular Formula | C13H8ClNO2 |
| Molecular Weight | 245.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole (CAS 67445-85-6) is a high-purity analytical reference standard with the molecular formula C13H8ClNO2 and a molecular weight of 245.66 g/mol.
The molecular framework of 5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole (C13H8ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8ClNO2 |
| Molecular Weight | 245.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 4-Chloro-6-oxo-1-(p-tolyl)-1,6-dihydropyridazine-3-carbonitrile (CAS 320419-35-0)
- 5-Fluoro-8-Quinolinesulfonyl Chloride (CAS 1997-50-8)
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- Oseltamivir Hydrochloride (CAS 204255-09-4)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
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