Lodoxamide lmpurity 18 CAS 67451-36-9
| CAS No. | 67451-36-9 |
| Molecular Formula | C11H8ClN3O7 |
| Molecular Weight | 329.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lodoxamide lmpurity 18.
CATO supplies Lodoxamide lmpurity 18 (CAS 67451-36-9), a pharmacopoeial impurity reference standard (molecular formula C11H8ClN3O7, MW 329.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Lodoxamide lmpurity 18 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 329.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lodoxamide lmpurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O7 |
| Molecular Weight | 329.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Lodoxamide Standards
- Lodoxamide lmpurity 19 (CAS 53882-26-1)
- Lodoxamide (CAS 53882-12-5)
- Lodoxamide impurity 23 (CAS CATO-C4X-294923)
- Lodoxamide lmpurity 13 (CAS 53882-13-6)
- Lodoxamide lmpurity 14 (CAS 67451-25-6)
- Lodoxamide lmpurity 15 (CAS 67605-91-8)
- Lodoxamide impurity 22 (CAS CATO-C4X-294922)
- Lodoxamide lmpurity 17 (CAS 84944-23-0)
Recommended Standards
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(dimethylamino)methylidene]-2,2-difluoroacetamide (CAS 1823194-67-7)
- 7-Chloro-6-fluoroisoquinolin-3-yl trifluoromethanesulfonate (CAS 2095607-17-1)
- (2-Bromo-4,5-dimethylthiophen-3-yl)(4-chlorophenyl)methanone (CAS 1380089-50-8)
- 3-Chloro-5-(4-fluorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439097-12-8)
- Bicalutamide EP Impurity J (CAS 90356-78-8)
- Vinpocetine Impurity 18 (CAS 18374-18-0)
- Risedronate EP Impurity B Sodium Salt (CAS 105462-23-5（free base）)
- 6-[(4-Methoxybenzyl)oxy]-1H-indazol-3-amine (CAS 1242152-57-3)
- Pitavastatin Impurity 36 (CAS CATO-C4X-103736)
- 2-Pentyl-1H-imidazole (CAS 33214-19-6)
- 2,7-Dimethyl-9H-carbazole (CAS 18992-65-9)
- 3-(2-Fluorobenzyl)quinazolin-4(3H)-one (CAS 141305-95-5)
- 3-[2-(Benzyloxy)ethoxy]-5-fluorophenylboronic acid (CAS 2377606-07-8)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com