Lodoxamide lmpurity 15 CAS 67605-91-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.67605-91-8
Molecular FormulaC15H15ClN2O8
Molecular Weight386.74 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lodoxamide lmpurity 15 CAS 67605-91-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 386.74 g/mol gives Lodoxamide lmpurity 15 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Lodoxamide lmpurity 15 (CAS 67605-91-8) is a certified pharmaceutical impurity reference standard with the molecular formula C15H15ClN2O8 and a molecular weight of 386.74 g/mol.

Lodoxamide lmpurity 15 (C15H15ClN2O8) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H15ClN2O8
Molecular Weight386.74 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Halogen ContentCl-containing
Nitrogen Atoms2

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