3-(2-Fluorophenyl)-2-(morpholinomethyl)quinazolin-4(3H)-one CAS 676630-60-7
| CAS No. | 676630-60-7 |
| Molecular Formula | C19H18FN3O2 |
| Molecular Weight | 339.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Fluorophenyl)-2-(morpholinomethyl)quinazolin-4(3H)-one (C19H18FN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-(2-Fluorophenyl)-2-(morpholinomethyl)quinazolin-4(3H)-one (CAS 676630-60-7), a certified reference material (molecular formula C19H18FN3O2, MW 339.36 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Fluorophenyl)-2-(morpholinomethyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18FN3O2 |
| Molecular Weight | 339.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- (E)-1-(4-fluorophenyl)-3-(4-(morpholine-4-carbonyl)phenyl)prop-2-en-1-one (CAS 866155-91-1)
- 3-[(4-Fluorophenyl)methyl]-4-hydroxy-1-[(3-methoxyphenyl)methyl]-1,2-dihydropyridin-2-one (CAS 478247-86-8)
- 3-(4-Fluorophenyl)-7-(naphthalen-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 692287-78-8)
- 1-(2-Fluorophenyl)-6-(thiophen-2-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011398-29-0)
- 1-((4-(4-Fluorophenyl)-6-methoxy-2H-chromen-3-yl)methyl)pyrrolidine (CAS 1370544-73-2)
- 10-(4-Fluorophenyl)-2,3,7,10-tetrahydro[1,4]dioxino[2,3-g]furo[3,4-b]quinolin-9(6H)-one (CAS 861208-10-8)
- N-(4-Fluorophenyl)-2-((4-(2-(methylamino)-2-oxoethyl)thiazol-2-yl)thio)acetamide (CAS 941980-81-0)
- Ethyl 3-{[4-(2-fluorophenyl)piperazine-1-carbothioyl]amino}propanoate (CAS 1022235-03-5)
Recommended Standards
- 2-Benzyl 1-(tert-butyl) (2R,3S,4R)-3-fluoro-4-hydroxypyrrolidine-1,2-dicarboxylate (CAS 2211115-86-3)
- 3-(4-Fluorobenzyl)-4-hydroxy-1-(2-methoxybenzyl)pyridin-2(1H)-one (CAS 477856-10-3)
- 2-Benzyl 1-(tert-butyl) (2R,3R,4S)-3-fluoro-4-hydroxypyrrolidine-1,2-dicarboxylate (CAS 2211115-85-2)
- 2-Benzyl 1-(tert-butyl) (2R,3R,4R)-3-fluoro-4-hydroxypyrrolidine-1,2-dicarboxylate (CAS 2211115-84-1)
- 3-(3,5-Dimethyl-1h-1,2,4-triazol-1-yl)-2-methyl-2-(methylamino)propanamide (CAS 1249926-12-2)
- 2-(6-Methylpyridin-2-yl)pyrrolidine-1-carbaldehyde (CAS 1352502-38-5)
- N-(3-Bromophenyl)-4-(N,N-dimethylsulfamoyl)benzamide (CAS 325977-90-0)
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- 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-65-1)
- 1H-pyrazol-1-amine (CAS 3994-46-5)
- Cobaltate(1-), bis[[2,3-butanedione 2,3-di(oximato-κN)](1-)]dichloro-, hydrogen (1:1), (OC-6-12)- (CAS 12107-63-0)
- 3-Chloro-4-iodophenol (CAS 855403-42-8)
- 3-Amino-5-(2-((tert-butoxycarbonyl)amino)ethyl)isonicotinic acid (CAS 1393550-22-5)
- MOTS-c Peptide (CAS 1627580-64-6)
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