1-(2-Fluorophenyl)-6-(thiophen-2-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid CAS 1011398-29-0
| CAS No. | 1011398-29-0 |
| Molecular Formula | C17H10FN3O2S |
| Molecular Weight | 339.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(2-Fluorophenyl)-6-(thiophen-2-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011398-29-0) is a high-purity analytical reference standard with the molecular formula C17H10FN3O2S and a molecular weight of 339.34 g/mol.
1-(2-Fluorophenyl)-6-(thiophen-2-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (C17H10FN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-(2-Fluorophenyl)-6-(thiophen-2-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H10FN3O2S |
| Molecular Weight | 339.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Ald-Ph-amido-PEG3-C-COOH (CAS 1007215-91-9)
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- Methyl 3-((tert-butoxycarbonyl)amino)-5-(2,2,2-trifluoroethyl)thiophene-2-carboxylate (CAS 2163771-84-2)
- IMidodicarbonic acid, 2-(3-nitro-2-pyridinyl)-, 1,3-bis(1,1-dimethylethyl) ester (CAS 1044758-23-7)
- 2-Amino-3-(trifluoromethyl)benzenethiol (CAS 131105-90-3)
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- 3-Cyclohexenecarbonylchloride (CAS 932-67-2)
- 1-((2-Bromophenyl)sulfonyl)piperazine hydrochloride (CAS 864759-56-8)
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- N-(5-Amino-2-fluorophenyl)-2-(4-methylphenoxy)-butanamide (CAS 1020056-85-2)
- 2-(Naphthalen-1-yl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 202828-12-4)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
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