Benzyl (1-chloro-2,2,2-trifluoroethyl)carbamate CAS 6776-48-3
| CAS No. | 6776-48-3 |
| Molecular Formula | C10H9ClF3NO2 |
| Molecular Weight | 267.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Benzyl (1-chloro-2,2,2-trifluoroethyl)carbamate (CAS 6776-48-3), molecular formula C10H9ClF3NO2 and molecular weight 267.63 g/mol, is a CATO reference standard with documented purity and traceability.
Benzyl (1-chloro-2,2,2-trifluoroethyl)carbamate (C10H9ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9ClF3NO2 |
| Molecular Weight | 267.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 6-Methylimidazo[1,2-a]pyridine-2-carboxylic Acid (CAS 80353-93-1)
- 334869-71-5 Neodymium(Iii) Acetate Hydrate (Reo) RTR-014010 (CAS 334869-71-5)
- 2-(Chloromethyl)-6-cyano-4-(difluoromethyl)pyridine-3-carboxaldehyde (CAS 1807085-59-1)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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