3-[3-(difluoromethoxy)phenyl]-3-oxopropanenitrile CAS 677713-03-0
| CAS No. | 677713-03-0 |
| Molecular Formula | C10H7F2NO2 |
| Molecular Weight | 211.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-[3-(difluoromethoxy)phenyl]-3-oxopropanenitrile (CAS 677713-03-0) is a high-purity analytical reference standard with the molecular formula C10H7F2NO2 and a molecular weight of 211.16 g/mol.
The molecular framework of 3-[3-(difluoromethoxy)phenyl]-3-oxopropanenitrile (C10H7F2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-[3-(difluoromethoxy)phenyl]-3-oxopropanenitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F2NO2 |
| Molecular Weight | 211.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluoromethoxy Standards
- 3-[2-(difluoromethoxy)phenyl]-3-oxopropanenitrile (CAS 1016690-71-3)
- 3-[4-(difluoromethoxy)phenyl]-3-oxopropanenitrile (CAS 1017036-63-3)
- 4-(Difluoromethoxy)quinolin-7-ol (CAS 1261458-12-1)
- 7-(Difluoromethoxy)quinolin-2-ol (CAS 1261458-20-1)
- 2-(Difluoromethoxy)quinolin-7-ol (CAS 1261475-30-2)
- 8-(Difluoromethoxy)quinolin-2(1H)-one (CAS 1261494-86-3)
- 4-(Difluoromethoxy)quinolin-6-ol (CAS 1261538-81-1)
- 2-(Difluoromethoxy)-8-hydroxyquinoline (CAS 1261628-91-4)
Recommended Standards
- 2-Cyano-3-(3,5-difluorophenyl)propionic Acid (CAS 2044707-20-0)
- 4-((Trifluoromethyl)thio)-1H-pyrrole-2-carboxylic acid (CAS 62665-40-1)
- 2-Cyano-3-(2,6-difluorophenyl)propionic Acid (CAS 2044707-22-2)
- 4-(Difluoromethyl)-1H-indole-2-carboxylic acid (CAS 2167142-20-1)
- 4,5-Dihydroxy-1-methyltetrahydro-2H-imidazole-2-thione (CAS 265986-74-1)
- 1,6-Dibromonaphthalen-2-yl diethylcarbamate (CAS 446307-68-2)
- N-((5-Oxo-2,5-dihydro-1H-pyrazol-3-yl)methyl)acetamide (CAS 33468-78-9)
- 2,5,6-Trichloro-4-methylnicotinonitrile (CAS 63195-39-1)
- (3E)-2,5-Diamino-2-(Fluoromethyl)-3-Pentenoic Acid (CAS 97501-13-8)
- 1-((2S,3R)-3-methoxypiperidin-2-yl)propan-2-one (CAS 39037-84-8)
- Amoxapine Impurity 2 (CAS CATO-C4X-25822)
- tert-Butyl ((1R,4S)-4-aminocyclopent-2-en-1-yl)carbamate (CAS 2440022-74-0)
- 2-tert-butyl-6-fluorophenol (CAS 133342-43-5)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
Why CATO?
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