N-(5-hydroxy-2-nitrophenyl)acetamide CAS 67915-26-8
| CAS No. | 67915-26-8 |
| Molecular Formula | C8H8N2O4 |
| Molecular Weight | 196.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-(5-hydroxy-2-nitrophenyl)acetamide (CAS 67915-26-8) is a high-purity analytical reference standard with the molecular formula C8H8N2O4 and a molecular weight of 196.16 g/mol.
N-(5-hydroxy-2-nitrophenyl)acetamide (C8H8N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O4 |
| Molecular Weight | 196.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- n-(4-Hydroxy-3-nitrophenyl)acetamide (CAS 51288-37-0)
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- N-(3-Hydroxy-4-nitrophenyl)acetamide (CAS 712-34-5)
- N-[(3-Hydroxy-2-pyridinyl)carbonyl]glycine (CAS 3458-69-3)
- Sodium (SP-4-1)-[29H,31H-phthalocyanine-2,9,16,23-tetrasulfonato(6-)-κN29,κN30,κN31,κN32]ferrate (CAS 41867-66-7)
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- 6-Methyl-1H-indazole (CAS 698-24-8)
- Oseltamivir Impurity 111 (CAS CATO-C4X-1720111)
- n-(1-((2,5-Dichlorophenyl)amino)-2-oxo-2-(p-tolyl)ethyl)furan-2-carboxamide (CAS 425631-08-9)
- 1-(2-Methylpropyl)-1h-1,2,3-triazole-4-carbaldehyde (CAS 1393539-81-5)
- Celecoxib Impurity 18 (CAS 2247197-67-5)
- Ethyl Allyl(2,2-dimethoxyethyl)carbamate (CAS 128740-02-3)
- 2-Cyano-N-(4-ethylphenyl)-3-(2-methoxyphenyl)propanamide (CAS 1260906-37-3)
- Tetrapeptide-3 (CAS 827306-97-8)
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