5-Chloro-1,7-naphthyridin-8-ol CAS 67967-13-9
| CAS No. | 67967-13-9 |
| Molecular Formula | C8H5ClN2O |
| Molecular Weight | 180.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-1,7-naphthyridin-8-ol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 180.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-Chloro-1,7-naphthyridin-8-ol (CAS 67967-13-9), molecular formula C8H5ClN2O and molecular weight 180.59 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-1,7-naphthyridin-8-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O |
| Molecular Weight | 180.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-Chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1000341-64-9)
- 8-Chloro-3,4-dihydroquinazolin-4-one (CAS 101494-95-5)
- 7-Chloro-4H-1-benzopyran-4-one (CAS 101860-74-6)
- 8-Chloro-1,7-naphthyridin-4(1H)-one (CAS 1018812-91-3)
- 4-Chloro-1h-indazole-3-carbaldehyde (CAS 102735-85-3)
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- 8-Chloro-1,5-naphthyridin-2(1H)-one (CAS 1092650-94-6)
- 5-Chloro-1H-indazole-7-carbaldehyde (CAS 1100213-27-1)
Recommended Standards
- 5-(3-Chlorophenyl)-2h-tetrazole (CAS 41421-28-7)
- 5-Chloro-1,8-naphthyridin-2(1H)-one (CAS 250264-28-9)
- 5-(2-Chlorophenyl)-1H-tetrazole (CAS 50907-46-5)
- 5-Chloro-1H-indene-1,2(3H)-dione (CAS 207554-23-2)
- 2-([1,1'-Biphenyl]-2-yl)acetaldehyde (CAS 90401-64-2)
- 2-(2-Chloro-4-(difluoromethyl)-5-hydroxypyridin-3-yl)acetic acid (CAS 1805058-37-0)
- [1,3]Dioxolo[4',5':5,6]benzo[1,2-c]isoxazole (CAS 158683-18-2)
- 2-(3,4-Difluoro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1025707-97-4)
- 5-(6-Aminopyridin-3-yl)thiophene-2-carboxylic acid (CAS 872838-44-3)
- 2-Fluoro-4,5,6,7-tetrahydrobenzo[d]thiazole (CAS 27225-19-0)
- 4-Benzyl-2-(piperidin-1-ylmethyl)morpholine (CAS 874881-17-1)
- 2-Cyclohexyl-5-methyl-2,4-dihydro-pyrazol-3-one (CAS 36210-76-1)
- (Chloromethyl)diethylphosphine oxide (CAS 37016-54-9)
- Bonemarrow-Derived Mesenchymal Stem Cells Affinity Peptide trifluoroacetate salt (CAS 683750-83-6)
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