5-Bromo-1,7-naphthyridin-8(7H)-one CAS 67967-14-0
| CAS No. | 67967-14-0 |
| Molecular Formula | C8H5BrN2O |
| Molecular Weight | 225.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Bromo-1,7-naphthyridin-8(7H)-one (CAS 67967-14-0), a certified reference material (molecular formula C8H5BrN2O, MW 225.04 g/mol) for analytical method development and quality control.
The molecular framework of 5-Bromo-1,7-naphthyridin-8(7H)-one (C8H5BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-1,7-naphthyridin-8(7H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5BrN2O |
| Molecular Weight | 225.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 6-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1000341-75-2)
- 4-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1000341-87-6)
- 5-Bromo-1,6-naphthyridin-2-ol (CAS 105276-96-8)
- 4-Bromo-2-(furan-3-yl)pyrimidine (CAS 1086381-95-4)
- 3-BroMo-1H-indazol-5-carbaldehyde (CAS 1086391-08-3)
- 3-Bromo-1H-indazole-6-carbaldehyde (CAS 1086391-14-1)
- 8-Bromo-1H-quinoxalin-2-one (CAS 1092563-82-0)
- 7-Bromo-1,5-naphthyridin-4(1H)-one (CAS 1151802-14-0)
Recommended Standards
- 5-(5-Bromopyridin-2-yl)oxazole (CAS 380380-74-5)
- 5-Bromo-1H-indazole-3-carbaldehyde (CAS 201227-38-5)
- 5-(4-bromophenyl)-1,2,4-oxadiazole (CAS 89892-25-1)
- 5-Bromo-1H-indene-1,3(2H)-dione (CAS 27611-39-8)
- 4-(2-(Acryloyloxy)ethoxy)-4-oxobutanoic acid (CAS 50940-49-3)
- 4-(3-Methylpyrrolidin-1-yl)benzoic acid (CAS 1291893-97-4)
- 3-Fluoro-4-(oxetan-3-yloxy)benzonitrile (CAS 1349717-11-8)
- 1’-(4-Nitrophenyl)-1,4’-bipiperidine (CAS 211247-61-9)
- 1,1,1,3,3,3-Hexamethyldisilazane (CAS 999-97-3)
- 1-(2-Bromo-5-chloropyridin-4-yl)ethanone (CAS 1823889-21-9)
- Thioctic acid Impurity 40 (CAS 91009-31-3)
- 1,2-Diazabicyclo[2.2.2]octan-3-one (CAS 1632-26-4)
- 5-Carboxy-2-fluoro-3-methoxyphenylboronic acid (CAS 2377609-80-6)
- Dulaglutide (CAS 923950-08-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com