N-(2-chloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-4-(trifluoromethyl)benzamide CAS 680215-13-8
| CAS No. | 680215-13-8 |
| Molecular Formula | C17H9ClF3NO3 |
| Molecular Weight | 367.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-(2-chloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-4-(trifluoromethyl)benzamide (CAS 680215-13-8), molecular formula C17H9ClF3NO3 and molecular weight 367.71 g/mol, is a CATO reference standard with documented purity and traceability.
N-(2-chloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-4-(trifluoromethyl)benzamide (C17H9ClF3NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H9ClF3NO3 |
| Molecular Weight | 367.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- (5-Bromo-2-chloropyridin-4-yl)(morpholino)methanone (CAS 1870258-51-7)
- N-(2-Furylmethyl)-N-(3-methylbutyl)amine (CAS 4462-11-7)
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- 3-(1-Methyl-2-oxo-1,2-dihydroquinolin-3-yl)acrylic acid (CAS 67735-45-9)
- Cefamandole Impurity 12 (CAS CATO-C4X-122112)
- N-Ethyl-3-(hydroxymethyl)piperidine-1-carboxamide (CAS 940077-81-6)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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