2-Chloro-3-((4-(trifluoromethoxy)phenyl)amino)naphthalene-1,4-dione CAS 763130-52-5
| CAS No. | 763130-52-5 |
| Molecular Formula | C17H9ClF3NO3 |
| Molecular Weight | 367.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-3-((4-(trifluoromethoxy)phenyl)amino)naphthalene-1,4-dione is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-3-((4-(trifluoromethoxy)phenyl)amino)naphthalene-1,4-dione (CAS 763130-52-5) is a high-purity analytical reference standard with the molecular formula C17H9ClF3NO3 and a molecular weight of 367.71 g/mol.
The molecular framework of 2-Chloro-3-((4-(trifluoromethoxy)phenyl)amino)naphthalene-1,4-dione (C17H9ClF3NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-3-((4-(trifluoromethoxy)phenyl)amino)naphthalene-1,4-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H9ClF3NO3 |
| Molecular Weight | 367.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 4.6-Dibromo-3-fluoro-2-nitrotoluene (CAS 1427503-00-1)
- 8-(4-Bromo-3-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 1704121-90-3)
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- Peramivir impurity 111 (CAS 2641684-79-7)
- 3-Cyclopropoxy-5-fluoro-2-nitropyridine (CAS 1243388-96-6)
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