N4-(4-chloro-2-methylphenyl)-2-chloroisonicotinamide CAS 680217-43-0
| CAS No. | 680217-43-0 |
| Molecular Formula | C13H10Cl2N2O |
| Molecular Weight | 281.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N4-(4-chloro-2-methylphenyl)-2-chloroisonicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N4-(4-chloro-2-methylphenyl)-2-chloroisonicotinamide (CAS 680217-43-0) is a high-purity analytical reference standard with the molecular formula C13H10Cl2N2O and a molecular weight of 281.14 g/mol.
Structurally, N4-(4-chloro-2-methylphenyl)-2-chloroisonicotinamide (C13H10Cl2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 281.14 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H10Cl2N2O |
| Molecular Weight | 281.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 2-Chloro-N-(3-chloro-2-methylphenyl)isonicotinamide (CAS 1019384-26-9)
- 2-Chloro-N-(2-chloro-4-methylphenyl)isonicotinamide (CAS 1040068-06-1)
- Bis(6-chloro-3-methylpyridin-2-yl)methanone (CAS 1414864-03-1)
- 4-Chloro-2-(4-chlorophenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine (CAS 1924486-83-8)
- (Z)-2-Chloro-N-(4-chlorophenyl)-N'-hydroxybenzene-1-carboximidamide (CAS 692288-04-3)
- 2-Chloro-1-(6-chloro-5-methyl-2-phenylpyrimidin-4-yl)ethanone (CAS 7505-83-1)
- 3-Chloro-N'-(4-chlorophenyl)-N-hydroxybenzimidamide (CAS 866049-32-3)
- 4-Chloro-N-(2-chlorobenzyl)picolinamide (CAS 923775-59-1)
Recommended Standards
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