8-([1,1'-Biphenyl]-4-ylamino)-2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one CAS 84283-08-9
| CAS No. | 84283-08-9 |
| Molecular Formula | C22H22N6O4 |
| Molecular Weight | 434.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-([1,1'-Biphenyl]-4-ylamino)-2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-([1,1'-Biphenyl]-4-ylamino)-2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one (CAS 84283-08-9) is a high-purity analytical reference standard with the molecular formula C22H22N6O4 and a molecular weight of 434.45 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, 8-([1,1'-Biphenyl]-4-ylamino)-2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 434.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-([1,1'-Biphenyl]-4-ylamino)-2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H22N6O4 |
| Molecular Weight | 434.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 6 |
Related Biphenyl Standards
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Recommended Standards
- 3,9-Bis[2-(3,5-diamino-2,4,6-triazaphenyl)ethyl]-2,4,8,10-tetraoxaspiro[5.5]undecane (CAS 22535-90-6)
- N-(4-methoxyphenyl)-3-(thiophen-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide (CAS 477845-18-4)
- (11β,16α)-21-(Acetyloxy)-9-fluoro-11,16,17-trihydroxy-pregna-1,4,14-triene-3,20-dione (CAS 131918-74-6)
- N-Nitroso Moxifloxacin D4 (CAS CATO-C4X-1074189)
- 3,4-Difluoro-5-nitrobenzenesulfonamide (CAS 1803826-57-4)
- (R)-4-((S)-1-hydroxyethyl)-1-((S)-1-(4-methoxyphenyl)ethyl)pyrrolidin-2-one (CAS 1319738-37-8)
- 6-(Cyclopentyloxy)-2-fluoropyridin-3-ol (CAS 1881296-17-8)
- (S)-4-(((Allyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)butanoic acid (CAS 171820-73-8)
- 2-{[4-(propan-2-yl)phenyl]sulfanyl}ethanimidamide hydrochloride (CAS 1394675-94-5)
- 3-(4-Chlorophenyl)-3-methoxyisoindolin-1-one (CAS 730-77-8)
- 5-(2-Fluorophenyl)-6,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-4(5H)-one (CAS 1708370-73-3)
- n-(2-(Cyclohex-1-en-1-yl)ethyl)-4-methylpentan-2-amine (CAS 628706-87-6)
- 6-Bromo-2-hydroxynaphthalene-1,4-dione (CAS 14848-40-9)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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