3-{5-[3,5-di(trifluoromethyl)phenyl]-2-furyl}-1-(2-hydroxyphenyl)prop-2-en-1-one CAS 680579-63-9
| CAS No. | 680579-63-9 |
| Molecular Formula | C21H12F6O3 |
| Molecular Weight | 426.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-{5-[3,5-di(trifluoromethyl)phenyl]-2-furyl}-1-(2-hydroxyphenyl)prop-2-en-1-one.
CATO supplies 3-{5-[3,5-di(trifluoromethyl)phenyl]-2-furyl}-1-(2-hydroxyphenyl)prop-2-en-1-one (CAS 680579-63-9), a certified reference material (molecular formula C21H12F6O3, MW 426.31 g/mol) for analytical method development and quality control.
The molecular framework of 3-{5-[3,5-di(trifluoromethyl)phenyl]-2-furyl}-1-(2-hydroxyphenyl)prop-2-en-1-one (C21H12F6O3) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H12F6O3 |
| Molecular Weight | 426.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related di Standards
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Recommended Standards
- Methyl 5-(4-bromobenzenesulfonamido)-1-benzothiophene-2-carboxylate (CAS 477847-43-1)
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- Ethyl 5-cyano-6-{[(2,4-dichlorophenyl)methyl]amino}-2-phenylpyridine-3-carboxylate (CAS 477866-13-0)
- 2-(4-Chlorophenyl)-3-[(4-chlorophenyl)sulfanyl]quinoline-4-carboxylic acid (CAS 338392-01-1)
- 3-(Pyrazin-2-yl)isoxazol-5-amine (CAS 1710853-32-9)
- Ethyl 5-methyl-3-(2-(piperidin-1-yl)acetamido)-1H-indole-2-carboxylate (CAS 296264-31-8)
- 5-Bromo-2-(4-fluorophenoxy)pyridine (CAS 936343-65-6)
- 5-(3-(2,4-Dichlorophenoxy)propyl)-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 792941-64-1)
- 3-(4-(Difluoromethyl)-2-nitrophenyl)propanal (CAS 1804239-34-6)
- JWH-145 (CAS 914458-19-8)
- N-(Naphthalen-2-yl)-N-phenyl-2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 337490-39-8)
- Ethyl 3-(N-(3,4-dimethylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate (CAS 932303-39-4)
- 5-(4-Iodophenyl)oxazol-2-amine (CAS 2091368-87-3)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
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