4-Bromo-5-hydroxyfuran-2(5H)-one CAS 68085-53-0
| CAS No. | 68085-53-0 |
| Molecular Formula | C4H3BrO3 |
| Molecular Weight | 178.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-5-hydroxyfuran-2(5H)-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Bromo-5-hydroxyfuran-2(5H)-one (CAS 68085-53-0), a certified reference material (molecular formula C4H3BrO3, MW 178.97 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, 4-Bromo-5-hydroxyfuran-2(5H)-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 178.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H3BrO3 |
| Molecular Weight | 178.97 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Br-containing |
Related Bromo Standards
- (3-Bromo-1,2,4-oxadiazol-5-yl)methanol (CAS 1781503-14-7)
- 3-Bromo-4-hydroxyfuran-2(5H)-one (CAS 21151-51-9)
- 4-Bromo-1-(fluoromethyl)-1H-pyrazole (CAS 1224194-56-2)
- 5-bromo-3-fluoro-1-methyl-pyrazole (CAS 1780764-54-6)
- 4-Bromo-5-fluoro-1-methyl-1H-pyrazole (CAS 1783510-78-0)
- 3-Bromo-5-fluoro-1-methyl-1H-pyrazole (CAS 1820608-53-4)
- 5-Bromo-4-fluoro-1-methyl-1H-imidazole (CAS 1823245-72-2)
- 5-Bromo-4-fluoro-1-methyl-1h-pyrazole (CAS 1935264-08-6)
Recommended Standards
- 4-(Bromomethyl)-1,3-dioxol-2-one (CAS 80715-25-9)
- 4-Acetamidophenylboronic Acid (CAS 101251-09-6)
- [4-(Methylcarbamoyl)phenyl]boronic Acid (CAS 121177-82-0)
- 3,4-Dichloro-3,4,4-trifluorobut-1-ene (CAS 374-26-5)
- Ethyl 2-ethyl-5-methyl-1,6-dioxaspiro[2.5]octane-2-carboxylate (CAS 1559664-92-4)
- tert-Butyl 4-(hydroxymethyl)-6,7-dihydro-5H-pyrido[3,4-c]azepine-8(9H)-carboxylate (CAS 1250998-82-3)
- N-(Chloroacetyl)4-(trifluoromethoxy)aniline (CAS 161290-85-3)
- 2-Acetylphenyl benzoate (CAS 4010-33-7)
- 6-Amino-3-chloromethyl-2-(trifluoromethyl)pyridine (CAS 1227595-56-3)
- Enarodustat Impurity 6 (CAS CATO-C4X-32286)
- 1-((3-Isopropyl-1,2,4-oxadiazol-5-yl)methyl)-1H-pyrazole-4-carboxylic acid (CAS 1270773-81-3)
- Methyl 3-(4-methoxybenzoyl)benzofuran-5-carboxylate (CAS 88673-78-3)
- 2-Isopropyl-4,5-dimethylimidazole (CAS 115152-71-1)
- β-Asp9-Tirzepatide (CAS CATO-CPTD788931)
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