3-(5-Amino-3-methyl-1H-pyrazol-1-yl)-4-chlorobenzenesulfonic acid CAS 68227-68-9
| CAS No. | 68227-68-9 |
| Molecular Formula | C10H10ClN3O3S |
| Molecular Weight | 287.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(5-Amino-3-methyl-1H-pyrazol-1-yl)-4-chlorobenzenesulfonic acid.
3-(5-Amino-3-methyl-1H-pyrazol-1-yl)-4-chlorobenzenesulfonic acid (CAS 68227-68-9) is a high-purity analytical reference standard with the molecular formula C10H10ClN3O3S and a molecular weight of 287.72 g/mol.
The molecular framework of 3-(5-Amino-3-methyl-1H-pyrazol-1-yl)-4-chlorobenzenesulfonic acid (C10H10ClN3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(5-Amino-3-methyl-1H-pyrazol-1-yl)-4-chlorobenzenesulfonic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN3O3S |
| Molecular Weight | 287.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazol-5-amine (CAS 618098-13-8)
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- 3-(3-Chloro-5-fluorophenyl)-4-cyanopropiophenone (CAS 898750-28-2)
- 4-(4-Chlorobenzyl)thiomorpholine-3,5-dione 1,1-dioxide (CAS 338421-33-3)
- 2-(tert-Butyl)-4-chlorothiazole (CAS 1893671-31-2)
- 2-(2-Chloro-3-(difluoromethyl)-5-fluoropyridin-4-yl)acetonitrile (CAS 1805061-06-6)
- Guanosine 5-Triphosphate Disodium Salt (CAS 56001-37-7)
- 3-(3-Methoxyphenyl)-3-(trifluoromethyl)-diaziridine (CAS 154187-45-8)
- (2-Cyclopropoxy-3,5-difluorophenyl)methanamine (CAS 2169474-40-0)
- Cefradine EP Impurity C (CAS CATO-C4X-12157)
- N1-methyl-N1-(1-(pyrazin-2-yl)ethyl)ethane-1,2-diamine (CAS 1342041-02-4)
- 5-(3-Aminopropyl)-4H-1,2,4-triazol-3-amine (CAS 113513-34-1)
- 1-(5-Amino-2-methylphenyl)pyrrolidine-2,5-dione (CAS 946768-88-3)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
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