5-Amino-4-chloro-2-(3-(difluoromethoxy)phenyl)pyridazin-3(2H)-one CAS 62270-15-9
| CAS No. | 62270-15-9 |
| Molecular Formula | C11H8ClF2N3O2 |
| Molecular Weight | 287.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-Amino-4-chloro-2-(3-(difluoromethoxy)phenyl)pyridazin-3(2H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 287.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 5-Amino-4-chloro-2-(3-(difluoromethoxy)phenyl)pyridazin-3(2H)-one (CAS 62270-15-9), a certified reference material (molecular formula C11H8ClF2N3O2, MW 287.65 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF2N3O2 |
| Molecular Weight | 287.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 3-Amino-5-chloro-2'-(trifluoromethoxy)biphenyl (CAS 1261554-01-1)
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- 4-Amino-6-(difluoromethyl)-5-nitropyridine-2-sulfonyl chloride (CAS 1806004-09-0)
- 5-Amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 94038-76-3)
- (5-Amino-1-(3-chlorophenyl)-1H-pyrazol-4-yl)(furan-2-yl)methanone (CAS 618091-66-0)
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Recommended Standards
- 2-Chloro-3-nitroanthracene-9,10-dione (CAS 35322-95-3)
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- 2-Chloro-1-nitroanthracene-9,10-dione (CAS 6374-88-5)
- Dimethyl2-(2-chloro-4-nitrophenyl)malonate (CAS 73088-10-5)
- N-(2-aminophenyl)acrylamide (CAS 139039-23-9)
- (S)-4-(Fluoromethylene)-5-oxopyrrolidine-2-carboxylic acid (CAS 728034-35-3)
- (S)-2-((2-(Trifluoromethyl)phenoxy)methyl)oxirane (CAS 134598-04-2)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)pyrrolidine (CAS 1156752-69-0)
- Tetrabutyl (2-(2-phenoxyethyl)propane-1,3-diyl)bis(phosphonate) (CAS 103486-79-9)
- 2-(2-bromoethyl)-6-phenyl-2,3-dihydropyridazin-3-one (CAS 22578-53-6)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-hydroxyethyl)-N-methylpiperidine-4-carboxamide (CAS 303150-26-7)
- 2-Isocyano-1-(1-piperidyl)ethanone (CAS 67434-28-0)
- 4-Bromo-1-(3-hydroxypropyl)pyrazole (CAS 925180-06-9)
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