3-(4-Fluorophenyl)-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-pyrazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one CAS 685107-17-9
| CAS No. | 685107-17-9 |
| Molecular Formula | C25H21FN4O3 |
| Molecular Weight | 444.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Fluorophenyl)-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-pyrazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one.
3-(4-Fluorophenyl)-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-pyrazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one (CAS 685107-17-9) is a high-purity analytical reference standard with the molecular formula C25H21FN4O3 and a molecular weight of 444.46 g/mol.
The molecular framework of 3-(4-Fluorophenyl)-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-pyrazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one (C25H21FN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Fluorophenyl)-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-pyrazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H21FN4O3 |
| Molecular Weight | 444.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluorophenyl Standards
- N-(2-(2-(4-Fluorophenyl)thiazol-4-yl)ethyl)-1-(4-(trifluoromethyl)phenyl)methanesulfonamide (CAS 1396631-04-1)
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)nicotinamide (CAS 400086-76-2)
- 2-(2-(2-((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)thiazol-4-yl)acetamido)benzamide (CAS 941874-54-0)
- 7-[4-(4-Fluorophenyl)piperazin-1-yl]-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477851-78-8)
- N-(6-(4-fluorophenyl)-2,5-dioxo-5,6-dihydro-2H-pyrano[3,2-c]pyridin-3-yl)-3-(trifluoromethyl)benzamide (CAS 341966-34-5)
- N-(2-(5-(2-Fluorophenyl)-1-(thiophene-2-carbonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide (CAS 923194-63-2)
- (Z)-2-{4-[(4-fluorophenyl)methoxy]-3-methoxyphenyl}-N-(4-methoxyphenyl)ethene-1-sulfonamide (CAS 339104-73-3)
- 4-[3-(2-Fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-2-yl]-N-[(4-fluorophenyl)methyl]benzamide (CAS 865658-48-6)
Recommended Standards
- 1-(3,5-Dichlorophenyl)-3-(dodecylsulfanyl)pyrrolidine-2,5-dione (CAS 329777-43-7)
- 3-Bromo-8-chloro-2-(3,4-dichlorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 866137-88-4)
- Z-Asp(OtBu)-ONp (CAS 17543-17-8)
- 4-Cumylphenyl diphenyl phosphate (CAS 34364-42-6)
- N-[(5-Methyl-1,2,4-oxadiazol-3-yl)methyl]-ethanamine (CAS 915923-33-0)
- 2-Aminoethyl 2-cyanoacetate hydrochloride (CAS 1147125-61-8)
- 1-[3-(Trifluoromethyl)phenyl]cyclopropanemethanamine (CAS 886365-96-4)
- (3-(Methylamino)piperidin-1-yl)(phenyl)methanone hydrochloride (CAS 1830923-34-6)
- Amoxapine-D8 (CAS 1189671-27-9)
- 3-Benzylsulfanyl-2-(tert-butoxycarbonylmethyl-amino)-propionic Acid tert-Butyl Ester (CAS 1331889-60-1)
- 4-((2-Oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)-N-(thiophen-2-ylmethyl)benzamide (CAS 339025-35-3)
- 5-Phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 142954-77-6)
- 4-Bromo-3-chloro-2-(difluoromethyl)-5-(trifluoromethyl)pyridine (CAS 1803691-04-4)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
Why CATO?
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