2-(2-(2-((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)thiazol-4-yl)acetamido)benzamide CAS 941874-54-0
| CAS No. | 941874-54-0 |
| Molecular Formula | C20H17FN4O3S2 |
| Molecular Weight | 444.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(2-(2-((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)thiazol-4-yl)acetamido)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(2-(2-((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)thiazol-4-yl)acetamido)benzamide (CAS 941874-54-0), molecular formula C20H17FN4O3S2 and molecular weight 444.50 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2-(2-((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)thiazol-4-yl)acetamido)benzamide (C20H17FN4O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H17FN4O3S2 |
| Molecular Weight | 444.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Fluorophenyl Standards
- N-(2-(2-(4-Fluorophenyl)thiazol-4-yl)ethyl)-1-(4-(trifluoromethyl)phenyl)methanesulfonamide (CAS 1396631-04-1)
- 3-(4-Fluorophenyl)-11,12-dimethoxy-8,9,13b,14-tetrahydro-6H-pyrazolo[5'',1'':2',3']pyrimido[4',5':4,5]pyrido[2,1-a]isoquinolin-6-one (CAS 685107-17-9)
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)nicotinamide (CAS 400086-76-2)
- 7-[4-(4-Fluorophenyl)piperazin-1-yl]-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477851-78-8)
- N-(6-(4-fluorophenyl)-2,5-dioxo-5,6-dihydro-2H-pyrano[3,2-c]pyridin-3-yl)-3-(trifluoromethyl)benzamide (CAS 341966-34-5)
- 1-(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 672950-45-7)
- 2-(4-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)-1-oxoisoquinolin-2(1H)-yl)acetic acid (CAS 685523-89-1)
- N-(2-(5-(2-Fluorophenyl)-1-(thiophene-2-carbonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide (CAS 923194-63-2)
Recommended Standards
- 2,5-Dimethoxy-N-(1-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)benzenesulfonamide (CAS 1396799-72-6)
- 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618075-97-1)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(benzo[d]thiazol-2-yl)propanoic acid (CAS 1263047-16-0)
- Boc-arg(mbS)-oh (CAS 58810-09-6)
- 2-((2,3-Dimethylphenyl)amino)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1197925-44-2)
- 2-(Difluoromethyl)-6-methyl-4-nitropyridine-3-acetonitrile (CAS 1805066-97-0)
- 1-(5-BROMO-7-NITRO-2,3-DIHYDRO-INDOL-1-YL)-ETHANONE 1-ACETYL-5-BROMO-7-NITRO-2,3-DIHYDRO-1H-INDOLE 1-ACETYL-5-BROMO-7-NITROINDOLE 1-ACETYL-5-BROMO-7-NITROINDOLINE 62368-07-4 BC003234 N-ACETYL-5-BROMO-7-NITRO-INDOLINE (CAS 62368-07-4)
- 3-Bromo-N-(2,2-dimethylthietan-3-yl)-5-methylpyridin-2-amine (CAS 1851916-79-4)
- Amisulpride Impurity 63 (CAS CATO-C4X-104563)
- 2-(2-(3-Chlorophenyl)-5-methyloxazol-4-yl)-N-hydroxyacetimidamide (CAS 1370601-76-5)
- 23945-50-8 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-oxo-2-thioxo- 1,2,3,4-Tetrahydro-4-oxo-2-thioxopyrimidine-5-carboxylic acid EINECS 245-948-8 2-Thiouracil-5-carboxylic acid (CAS 23945-50-8)
- 6-Ethyl-3-(furan-2-ylmethyl)-2-mercaptothieno[2,3-d]pyrimidin-4(3h)-one (CAS 743452-29-1)
- 361189-64-2 alpha-Hydroxy-omega-carboxy t-butyl ester hexa(ethylene glycol) MFCD13185017 HO-PEG6-CO-OtBu (CAS 361189-64-2)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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