11-((4-Chlorophenyl)sulfonyl)-2,3-dimethoxy-5,11,12,12a-tetrahydropyrazolo[3',4':4,5]pyrido[2,1-a]isoquinolin-8(6H)-one CAS 685107-92-0
| CAS No. | 685107-92-0 |
| Molecular Formula | C22H20ClN3O5S |
| Molecular Weight | 473.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
11-((4-Chlorophenyl)sulfonyl)-2,3-dimethoxy-5,11,12,12a-tetrahydropyrazolo[3',4':4,5]pyrido[2,1-a]isoquinolin-8(6H)-one (CAS 685107-92-0) is a high-purity analytical reference standard with the molecular formula C22H20ClN3O5S and a molecular weight of 473.93 g/mol.
The molecular framework of 11-((4-Chlorophenyl)sulfonyl)-2,3-dimethoxy-5,11,12,12a-tetrahydropyrazolo[3',4':4,5]pyrido[2,1-a]isoquinolin-8(6H)-one (C22H20ClN3O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H20ClN3O5S |
| Molecular Weight | 473.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- Ethyl 4-((4-chlorophenyl)sulfonyl)-6-(ethylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate (CAS 866051-00-5)
- (E)-2-{4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl}-N-[(3-methoxyphenyl)methyl]ethene-1-sulfonamide (CAS 339018-73-4)
- 3-[(4-Chlorophenyl)methanesulfinyl]-5-[(naphthalen-1-yloxy)methyl]-4-phenyl-4H-1,2,4-triazole (CAS 956148-54-2)
- 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3,4-dichlorophenyl)acetamide (CAS 338957-24-7)
- 2-(2-(4-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3,4-dichlorophenyl)acetamide (CAS 339277-92-8)
- (E)-({5-[(4-chlorophenyl)sulfanyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}methylidene)amino 2-chlorobenzoate (CAS 321533-89-5)
- 1-(3-Chlorophenyl)-4-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl)piperazine (CAS 477869-38-8)
- 2-((4,5-Bis(4-chlorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 763088-51-3)
Recommended Standards
- Lixivaptan - API Standards (CAS 168079-32-1)
- 2-(4-(Benzyloxy)-2-chlorobenzoyl)-N-tosylhydrazine-1-carboxamide (CAS 478039-98-4)
- 1-(4-Benzhydrylpiperazin-1-yl)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)ethan-1-one (CAS 691869-09-7)
- 4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-[[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy]quinazoline (CAS 848942-61-0)
- (S)-Methyl 2-(chloromethyl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylate (CAS 2230200-76-5)
- (3-((Diethylcarbamoyl)oxy)pyridin-4-yl)boronic acid (CAS 868826-84-0)
- Hexahydro-1H-pyrazino[1,2-a]pyrazine-1,4(6H)-dione (CAS 1256642-92-8)
- 7-Acetyl-4-methoxybenzo[d]thiazol-2(3H)-one (CAS 662111-32-2)
- 5-Cyclopentyl-3-phenyl-1,2-oxazole-4-carboxylic acid (CAS 1985536-79-5)
- Cabozantinib Impurity 9 (CAS 18721-64-7)
- 3-Morpholino-1-(naphthalen-2-yl)propan-1-one (CAS 27478-04-2)
- Methyl 2-(3-chlorobenzamido)thiophene-3-carboxylate (CAS 338750-43-9)
- 3-Bromo-5-(methylthio)phenol (CAS 1243394-57-1)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com