Dopamine Impurity 81 CAS 68929-11-3
| CAS No. | 68929-11-3 |
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Dopamine Impurity 81 (CAS 68929-11-3), a pharmacopoeial impurity reference standard (molecular formula C8H9NO3, MW 167.16 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dopamine Impurity 81 (C8H9NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >9% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 1 |
Related Dopamine Standards
- Dopamine Impurity 17 (CAS 1129-53-9)
- Dopamine Impurity 82 (CAS 5663-54-7)
- Dopamine Impurity 83 (CAS CATO-C4X-190883)
- Dopamine Impurity 84 (CAS CATO-C4X-190884)
- Dopamine Impurity 99 (CAS CATO-C4X-190899)
- Dopamine EP Impurity A (CAS 3213-30-7)
- Dopamine EP Impurity B (CAS 554-52-9)
- Dopamine Impurity 43 (CAS 52846-75-0)
Recommended Standards
- Nicorandil Impurity 26 (CAS 14906-63-9)
- Pyridoxine Impurity 16 (CAS 58947-70-9)
- Noradrenalone EP Impurity B (CAS 499-61-6)
- Norepinephrine Impurity 20 (CAS 67896-55-3)
- Lovastatin EP Impurity A (CAS 73573-88-3)
- Cefcapene Impurity 30 (CAS 28242-91-3)
- Nebivolol Impurity 74 (CAS CATO-C4X-196874)
- n-Methyl-2-(4-methylpiperidin-1-yl)acetamide (CAS 1071400-91-3)
- 5-(Aminomethyl)furan-2-carbonitrile Hydrochloride (CAS 203792-32-9)
- N-Benzyl-2-[(2-chlorophenyl)sulfanyl]-N-methylacetamide (CAS 339097-69-7)
- 5-(Bromomethyl)-2,3-dimethylpyrazine (CAS 1339947-51-1)
- Bilastine Impurity 44 (CAS CATO-C4X-225344)
- Allylglycinehydrochloride (CAS 3182-78-3)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com