Dopamine Impurity 17 CAS 1129-53-9
| CAS No. | 1129-53-9 |
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Dopamine Impurity 17 (CAS 1129-53-9, C8H9NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dopamine Impurity 17 (C8H9NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 167.16 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Dopamine Standards
- Dopamine Impurity 81 (CAS 68929-11-3)
- Dopamine Impurity 82 (CAS 5663-54-7)
- Dopamine Impurity 83 (CAS CATO-C4X-190883)
- Dopamine Impurity 84 (CAS CATO-C4X-190884)
- Dopamine Impurity 99 (CAS CATO-C4X-190899)
- Dopamine EP Impurity A (CAS 3213-30-7)
- Dopamine EP Impurity B (CAS 554-52-9)
- Dopamine Impurity 43 (CAS 52846-75-0)
Recommended Standards
- Nicorandil Impurity 26 (CAS 14906-63-9)
- Pyridoxine Impurity 16 (CAS 58947-70-9)
- Noradrenalone EP Impurity B (CAS 499-61-6)
- Norepinephrine Impurity 20 (CAS 67896-55-3)
- Paraben Impurity 8 (CAS CATO-C4X-25698)
- Droperidol Impurity 17 (CAS 466118-73-0)
- Fosfomycin Impurity 22 (CAS CATO-C4X-131622)
- 2-(4-Ethoxyphenyl)propanoic acid (CAS 91970-86-4)
- Benzyl N-butyl-N-(4-hydroxyphenyl)carbamate (CAS 1881290-24-9)
- Besudil Impurity 12 (CAS CATO-C4X-298812)
- Methyl 2-[(2-{[2,4-dichloro-5-(2-methoxyethoxy)phenyl]carbamoyl}-2-hydroxy-2-methylethyl)sulfanyl]benzoate (CAS 866136-35-8)
- Ceftaroline Impurity 5 (CAS CATO-C4X-14835)
- Methyl 4,5-dibromo-3-fluorothiophene-2-carboxylate (CAS 395664-58-1)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
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