Ceftolozane CAS 689293-68-3
| CAS No. | 689293-68-3 |
| Molecular Formula | C23H30N12O8S2 |
| Molecular Weight | 666.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ceftolozane.
Ceftolozane (CAS 689293-68-3) is a high-purity analytical reference standard with the molecular formula C23H30N12O8S2 and a molecular weight of 666.69 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Ceftolozane is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 666.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H30N12O8S2 |
| Molecular Weight | 666.69 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 12 |
| Sulfur Atoms | 2 |
Related Ceftolozane Standards
- Ceftolozane impurity 7 (CAS 1956303-45-9)
- Ceftolozane impurity 8 (CAS 1956303-44-8)
- Ceftolozane impurity 9 (CAS 1852466-67-1)
- Ceftolozane Impurity 34 (CAS CATO-C4X-240634)
- Ceftolozane Impurity 35 (CAS CATO-C4X-240635)
- Ceftolozane Impurity 18 (CAS CATO-C4X-240618)
- Ceftolozane Impurity 29 (CAS CATO-C4X-240629)
- Ceftolozane Impurity 17 (CAS CATO-C4X-240617)
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