3-(2-Aminopyrimidin-4-yl)-1-(4-chlorophenyl)pyridazin-4(1H)-one CAS 690211-52-0

Purity 97%+In StockPharmaceutical Standards
CAS No.690211-52-0
Molecular FormulaC14H10ClN5O
Molecular Weight299.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2-Aminopyrimidin-4-yl)-1-(4-chlorophenyl)pyridazin-4(1H)-one CAS 690211-52-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 299.72 g/mol gives 3-(2-Aminopyrimidin-4-yl)-1-(4-chlorophenyl)pyridazin-4(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(2-Aminopyrimidin-4-yl)-1-(4-chlorophenyl)pyridazin-4(1H)-one (CAS 690211-52-0) is a high-purity analytical reference standard with the molecular formula C14H10ClN5O and a molecular weight of 299.72 g/mol.

The molecular framework of 3-(2-Aminopyrimidin-4-yl)-1-(4-chlorophenyl)pyridazin-4(1H)-one (C14H10ClN5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H10ClN5O
Molecular Weight299.72 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentCl-containing
Nitrogen Atoms5

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