2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one CAS 691858-21-6
| CAS No. | 691858-21-6 |
| Molecular Formula | C18H16Cl2F3N3O |
| Molecular Weight | 418.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one (CAS 691858-21-6), molecular formula C18H16Cl2F3N3O and molecular weight 418.24 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 418.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16Cl2F3N3O |
| Molecular Weight | 418.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- (4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)piperazin-1-yl)(4-chlorophenyl)methanone (CAS 1311278-56-4)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-(4-chlorobenzyl) oxime (CAS 250714-04-6)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)piperidine-4-carboxamide (CAS 337919-69-4)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-1-(4-chlorophenyl)ethan-1-one (CAS 338979-09-2)
- (R)-4-chloro-6-(1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-2-amine (CAS 1675978-29-6)
- (3-(2-Chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)(5-(chlorodifluoromethyl)-2,3-dihydro-1H-1,4-diazepin-1-yl)methanone (CAS 439096-47-6)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-cyanopropan-2-yl 4-chlorobenzoate (CAS 338968-33-5)
- (E)-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methoxy}({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene})amine (CAS 400081-12-1)
Recommended Standards
- 6-Bromo-2-(3,4,5-trimethoxyphenyl)quinoline-4-carboxylic acid (CAS 351329-63-0)
- 9-(2,5-Difluorophenyl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a][1,8]naphthyridine (CAS 338962-28-0)
- N'-[(1E)-(4-Ethylphenyl)methylidene]-6-iodoimidazo[1,2-a]pyridine-2-carbohydrazide (CAS 939762-08-0)
- Dimethyl 5-(3,4-dichlorophenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2,2-dioxide (CAS 107124-27-6)
- 5,5-Dimethylpyrrolidine-2-carboxylic acid hydrochloride (CAS 1796882-98-8)
- Diethyl 2-((2-ethoxy-2-oxoethyl)thio)succinate (CAS 909772-87-8)
- (Dibenzofuran-2-yl)-2-oxobutanoic Acid (CAS 885951-79-1)
- (6r)-6-(Hydroxymethyl)piperidin-2-one (CAS 213532-95-7)
- 4-Acetamido-2-fluoro-5-methylbenzenesulfonyl chloride (CAS 71245-49-3)
- 3-(Ethylthio)picolinonitrile (CAS 342816-54-0)
- 1-(2-Chloroethyl)pyridin-2(1h)-one (CAS 51323-39-8)
- Boc-Alanine Pentafluorophenyl Ester (CAS 50903-48-5)
- N-((2,4-difluorophenyl)carbamothioyl)thiophene-2-carboxamide (CAS 900769-45-1)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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