N'-[(1E)-[6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene]benzohydrazide CAS 691884-01-2
| CAS No. | 691884-01-2 |
| Molecular Formula | C19H13BrN4OS |
| Molecular Weight | 425.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N'-[(1E)-[6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene]benzohydrazide.
N'-[(1E)-[6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene]benzohydrazide (CAS 691884-01-2) is a high-purity analytical reference standard with the molecular formula C19H13BrN4OS and a molecular weight of 425.30 g/mol.
The molecular framework of N'-[(1E)-[6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene]benzohydrazide (C19H13BrN4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N'-[(1E)-[6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene]benzohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H13BrN4OS |
| Molecular Weight | 425.30 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
- 3-Amino-N-(3-bromophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-35-6)
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- 2-((4-(4-Bromophenyl)thiazol-2-yl)amino)-6-phenylpyrimidin-4(1H)-one (CAS 88067-22-5)
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