4,6-Bis((4-chlorobenzyl)thio)cinnoline CAS 6957-46-6
| CAS No. | 6957-46-6 |
| Molecular Formula | C22H16Cl2N2S2 |
| Molecular Weight | 443.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,6-Bis((4-chlorobenzyl)thio)cinnoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4,6-Bis((4-chlorobenzyl)thio)cinnoline (CAS 6957-46-6) is a high-purity analytical reference standard with the molecular formula C22H16Cl2N2S2 and a molecular weight of 443.41 g/mol.
The molecular framework of 4,6-Bis((4-chlorobenzyl)thio)cinnoline (C22H16Cl2N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4,6-Bis((4-chlorobenzyl)thio)cinnoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16Cl2N2S2 |
| Molecular Weight | 443.41 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Bis Standards
- 4,6-Bis((2-chlorobenzyl)thio)cinnoline (CAS 6957-47-7)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-(3,4-dichlorobenzyl)-1H-pyrazole (CAS 477713-45-4)
- N-(4-chlorobenzyl)-2-((3-oxo-2-(thiophen-2-ylmethyl)isoindolin-1-yl)thio)acetamide (CAS 866008-25-5)
- 2-((2-Chlorobenzyl)thio)-6-(4-methoxyphenyl)-4-phenylnicotinonitrile (CAS 332175-72-1)
- 2-((4-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-phenylnicotinonitrile (CAS 330551-80-9)
- 3-((4-Chlorobenzyl)sulfinyl)-4-ethyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 956607-36-6)
- 4-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-02-8)
- 2-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-22-2)
Recommended Standards
- Ningnanmycin (CAS 156410-09-2)
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- Folic Acid Impurity 14 (CAS 4033-27-6)
- 4-(2-(1,2-Dimethyl-1H-indol-3-yl)-3,3,4,4,5,5-hexafluorocyclopent-1-en-1-yl)-5-methylthiophene-2-carbaldehyde (CAS 1400275-94-6)
- 1-(4-Chlorophenyl)-4-methyl-1H-pyrazol-5-amine (CAS 1071125-31-9)
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- 2-Nitropyridin-3-yl 4-methylbenzene-1-sulfonate (CAS 1240527-92-7)
- Ethyl (4-chlorophenyl)glycinate (CAS 2521-89-3)
- Methyl 2-methyl-[1,1'-biphenyl]-3-carboxylate (CAS 1329496-87-8)
- Bromocyclohexane (CAS 108-85-0)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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