4,6-Bis((2-chlorobenzyl)thio)cinnoline CAS 6957-47-7
| CAS No. | 6957-47-7 |
| Molecular Formula | C22H16Cl2N2S2 |
| Molecular Weight | 443.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4,6-Bis((2-chlorobenzyl)thio)cinnoline (CAS 6957-47-7), a certified reference material (molecular formula C22H16Cl2N2S2, MW 443.41 g/mol) for analytical method development and quality control.
The molecular framework of 4,6-Bis((2-chlorobenzyl)thio)cinnoline (C22H16Cl2N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16Cl2N2S2 |
| Molecular Weight | 443.41 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Bis Standards
- 4,6-Bis((4-chlorobenzyl)thio)cinnoline (CAS 6957-46-6)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-(3,4-dichlorobenzyl)-1H-pyrazole (CAS 477713-45-4)
- N-(4-chlorobenzyl)-2-((3-oxo-2-(thiophen-2-ylmethyl)isoindolin-1-yl)thio)acetamide (CAS 866008-25-5)
- 2-((2-Chlorobenzyl)thio)-6-(4-methoxyphenyl)-4-phenylnicotinonitrile (CAS 332175-72-1)
- 2-((4-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-phenylnicotinonitrile (CAS 330551-80-9)
- 3-((4-Chlorobenzyl)sulfinyl)-4-ethyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 956607-36-6)
- 4-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-02-8)
- 2-Chlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-22-2)
Recommended Standards
- 4-(6-Bromo-1H-indol-3-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 2126164-27-8)
- 4-(2-(1,2-Dimethyl-1H-indol-3-yl)-3,3,4,4,5,5-hexafluorocyclopent-1-en-1-yl)-5-methylthiophene-2-carbaldehyde (CAS 1400275-94-6)
- Ningnanmycin (CAS 156410-09-2)
- 6-((2-(Benzo[d][1,3]dioxol-5-yl)-2-oxoethyl)thio)-4-(trifluoromethyl)-[2,4'-bipyridine]-5-carbonitrile (CAS 625377-04-0)
- 2-Bromo-4-iodo-6-methylphenol (CAS 1820641-98-2)
- Methyl 3-(pyrrolidin-1-yl)cyclobutane-1-carboxylate (CAS 2113813-14-0)
- (3-Chloro-4-methoxybenzyl)hydrazine (CAS 887596-31-8)
- 2-Amino-1-(azepan-1-yl)propan-1-one hydrochloride (CAS 1236260-29-9)
- 2-(2-Isopropoxyethyl)piperidine (CAS 1018628-43-7)
- Methyl 4-((2-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)thio)butanoate (CAS 478046-04-7)
- 5-bromo-2-methyl-indazole-3-carbaldehyde (CAS 1251023-52-5)
- Spectinomycin Sulfate Tetrahydrate (CAS 64058-48-6)
- (R)-3-Amino-3-(4-bromophenyl)propan-1-ol (CAS 1213037-93-4)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com