4-Amino-2,4-dihydro-5-(tetrahydro-2-furanyl)-3H-1,2,4-triazole-3-thione CAS 697245-67-3

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-Amino-2,4-dihydro-5-(tetrahydro-2-furanyl)-3H-1,2,4-triazole-3-thione (CAS 697245-67-3), molecular formula C6H10N4OS and molecular weight 186.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Amino-2,4-dihydro-5-(tetrahydro-2-furanyl)-3H-1,2,4-triazole-3-thione (C6H10N4OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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