Fludarabine Phosphate EP Impurity H CAS 548774-57-8
| CAS No. | 548774-57-8 |
| Molecular Formula | C10H10FN5O3 |
| Molecular Weight | 267.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fludarabine Phosphate EP Impurity H (CAS 548774-57-8) is a certified pharmaceutical impurity reference standard with the molecular formula C10H10FN5O3 and a molecular weight of 267.22 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Fludarabine Phosphate EP Impurity H is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Fludarabine Phosphate EP Impurity H meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10FN5O3 |
| Molecular Weight | 267.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fludarabine Standards
- Fludarabine Phosphate EP Impurity H (CAS CATO-C4X-18468)
- Fludarabine Phosphate EP Impurity E (CAS 21679-14-1)
- Fludarabine Phosphate Impurity 22 (CAS 13276-42-1)
- Fludarabine Impurity 20 (CAS CATO-C4X-184620)
- Fludarabine Phosphate EP Impurity I (CAS 7561-54-8)
- Fludarabine Phosphate EP Impurity I (CAS 62314-91-4)
- Fludarabine Phosphate EP Impurity A (CAS 62314-92-5)
- Fludarabine Phosphate (CAS 75607-67-9)
Recommended Standards
- 6-Cyclopropyl-1-(2,2-difluoroethyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018143-42-4)
- Dolutegravir Impurity 19 (CAS 1916490-96-4)
- tert-Butyl (3-formyl-4-nitrophenyl) carbonate (CAS 1027818-09-2)
- Creatine Phosphate Impurity 3 (CAS CATO-C4X-12093)
- Rupatadine impurity 1 (CAS 1118754-56-5)
- Dotinurad Impurity 132 (CAS CATO-C4X-2494132)
- Ticarcillin EP Impurity A (CAS 36041-93-7)
- Propyl[(3,4,5-trimethoxyphenyl)methyl]amine hydrochloride (CAS 1158256-01-9)
- (E)-4-(4-nitrostyryl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline (CAS 866133-32-6)
- Deltamethrin Impurity 1 (Mixture of Diastereomers) (CAS 59952-39-5)
- 2,2,2-Trichloro-N,N-dimethylacetamide (CAS 7291-33-0)
- Phosphoric Acid Dioctyl Ester (CAS 3115-39-7)
- 2,5’-Dibromo-2’-fluoropropiophenone (CAS 1221684-53-2)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
Why CATO?
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