Saxagliptin Impurity N1 CAS 700376-58-5
| CAS No. | 700376-58-5 |
| Molecular Formula | C6H10N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Saxagliptin Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Saxagliptin Impurity N1 (CAS 700376-58-5, C6H10N2OC2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Saxagliptin Impurity N1 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 240.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C6H10N2O C2HF3O2 |
| Molecular Weight | 240.18 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Saxagliptin Standards
- Saxagliptin Impurity N1 (CAS 102502-64-7)
- Saxagliptin Hydrochloride Dihydrate (CAS 1073057-20-1)
- Saxagliptin Impurity N52 (CAS 1194836-75-3)
- Saxagliptin Cyclic Imidine Impurity (CAS 1194836-77-5)
- (±)-Saxagliptin-13C3 (acetyl-13C2,cyclopropyl-3-13C) (CAS 1246812-44-1)
- Saxagliptin-15N,D2 Hydrochloride (CAS 1309934-06-2)
- Saxagliptin Impurity 60 Mesylate (CAS 1312338-82-1)
- Saxagliptin Impurity 6 (CAS 1334321-39-9)
Recommended Standards
- Nicardipine Impurity 36 (CAS 115972-93-5)
- Cimetidine EP Impurity I (CAS 38585-62-5)
- Abemaciclib Impurity 181 (CAS CATO-C4X-2937181)
- N-(2,4-dimethoxyphenyl)-2-(piperazin-1-yl)acetamide (CAS 946666-19-9)
- (+/-)-4-methyl-4-vinylazetidin-2-one 20012-94-6 4-ethenyl-4-methylazetidin-2-one (CAS 20012-94-6)
- 2-((2-Chlorobenzyl)amino)-2-oxoethyl 5-bromofuran-2-carboxylate (CAS 386277-36-7)
- 1-(2-Morpholinoethyl)guanidine (CAS 69602-62-6)
- 1-Ethyl-N-(5-methylisoxazol-3-yl)-1H-pyrazole-4-carboxamide (CAS 515122-60-8)
- 4-Methyl-3-(2-methylbenzenesulfonyl)-2-[(2-methylprop-2-en-1-yl)oxy]-6-phenylpyridine (CAS 344278-79-1)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com