Vidarabine Impurity 1 CAS 7013-16-3
| CAS No. | 7013-16-3 |
| Molecular Formula | C10H12N4O5 |
| Molecular Weight | 268.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 268.23 g/mol gives Vidarabine Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Vidarabine Impurity 1 (CAS 7013-16-3, C10H12N4O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Vidarabine Impurity 1 (C10H12N4O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 268.23 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vidarabine Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N4O5 |
| Molecular Weight | 268.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 4 |
Related Vidarabine Standards
Recommended Standards
- Inosine (CAS 58-63-9)
- L-Inosine (CAS 21138-24-9)
- 1,4-Dihydro-4-|A-D-ribofuranosyl-5H-1,2,3-triazolo[4,5-b]pyridin-5-one 4-(|A-D-Ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one 59892-40-9 (CAS 59892-40-9)
- Inosine Impurity 2 (CAS 52678-79-2)
- Naltrexone impurity 41 (CAS CATO-C4X-147541)
- Tetracaine Impurity 37 (CAS 512175-79-0 (free base))
- Relebactam Impurity 70 (CAS 1822463-49-9)
- 4-Aminonaphthalen-1-ol (CAS 2834-90-4)
- N-(1-benzyl-3-cyano-4,5-dimethyl-1H-pyrrol-2-yl)-3-methylbenzamide (CAS 478032-97-2)
- 2-Methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride (CAS 63937-92-8)
- 3-((4-Chlorophenoxy)methyl)-5-(methylthio)-4-phenyl-4H-1,2,4-triazole (CAS 116454-44-5)
- Ethyl 4-amino-3-methoxy-1-methyl-1H-pyrrole-2-carboxylate (CAS 389615-05-8)
- 2-methyl-1-{pyrrolo[2,1-f][1,2,4]triazin-7-yl}propan-1-one (CAS 1557912-94-3)
- (β-Asp5)-Delta-Sleep Inducing Peptide (CAS 82602-88-8)
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