Vidarabine Impurity 10 CAS 26524-56-1
| CAS No. | 26524-56-1 |
| Molecular Formula | C10H14N5O7P |
| Molecular Weight | 347.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Vidarabine Impurity 10 (CAS 26524-56-1, C10H14N5O7P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Vidarabine Impurity 10 (C10H14N5O7P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vidarabine Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N5O7P |
| Molecular Weight | 347.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 5 |
Related Vidarabine Standards
Recommended Standards
- Bucladesine Impurity 6 (CAS 16955-44-5)
- Bucladesine Impurity 11 (CAS 21138-49-8)
- S-Adenosyl-L-Methionine Impurity 12 (CAS 84-21-9)
- S-Adenosyl-L-Methionine Impurity 11 (CAS 81012-86-4)
- Entecavir Impurity 27 (CAS CATO-C4X-107727)
- Diquafosol Impurity 25 (CAS CATO-C4X-214925)
- Thymidine Impurity 2 (CAS CATO-C4X-32972)
- 1-(Piperidin-4-ylmethyl)piperidin-4-ol dihydrochloride (CAS 1220037-59-1)
- Tegoprazan Impurity 120 (CAS CATO-C4X-2297120)
- 4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol (CAS 612501-52-7)
- N-Benzyl-2-((3-(3-chlorophenyl)-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-yl)thio)acetamide (CAS 536713-36-7)
- 2,2-Bis(hydroxymethyl)-4-methylmorpholin-3-one (CAS 1456821-63-8)
- methyl 2-hydroxy-3-methoxypropanoate (CAS 54927-70-7)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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