4-Chloro-2-(Chloromethyl)-1-Methoxybenzene CAS 7035-11-2
| CAS No. | 7035-11-2 |
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-(Chloromethyl)-1-Methoxybenzene (CAS 7035-11-2), molecular formula C8H8Cl2O and molecular weight 191.05 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-Chloro-2-(Chloromethyl)-1-Methoxybenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 191.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-2-(Chloromethyl)-1-Methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 1-chloro-2-(chloromethyl)-4-methoxybenzene (CAS 101079-83-8)
- 2-Chloro-4-methoxybenzyl chloride (CAS 101080-63-1)
- 2-Chloro-1-(3-chloro-phenyl)-ethanol (CAS 106262-93-5)
- 1-Chloro-4-(2-chloroethoxy)benzene (CAS 13001-28-0)
- 2-Chloro-4-(chloromethyl)-1-methoxybenzene (CAS 13719-57-8)
- 1-Chloro-4-(chloromethyl)-2-methoxybenzene (CAS 13726-18-6)
- (R)-2-chloro-1-(3-chlorophenyl)ethanol (CAS 142763-10-8)
- (S)-2-Chloro-1-(3-chlorophenyl)ethanol (CAS 174699-78-6)
Recommended Standards
- 4,5-dichloro-2-ethylphenol (CAS 52016-71-4)
- 2,4-Dichloro-3,5-Dimethylphenol (CAS 133-53-9)
- 4-(Dichloromethyl)-4-methylcyclohexa-2,5-dien-1-one (CAS 6611-78-5)
- (2,6-Dichloro-3-methylphenyl)hydrazine (CAS 1099660-40-8)
- (E)-N-(Pyridin-2-ylmethylene)aniline (CAS 40468-86-8)
- 2-Ethyl-N-((1-(4-fluorophenyl)-1H-tetrazol-5-yl)methyl)butanamide (CAS 897623-34-6)
- 4-Hydroxy-2-methyl-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 64321-67-1)
- 3,4,7,9-Tetramethyl-1,4-dihydro-[1,2,4]triazino[3,4-f]purine-6,8(7h,9h)-dione (CAS 382646-12-0)
- 5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one (CAS 304468-42-6)
- N-Methyl-1-(1-methylpiperidin-3-yl)methanamine (CAS 639078-61-8)
- (2-Ethoxy-1-iodo-2-oxoethyl)triphenylphosphonium iodide (CAS 111598-99-3)
- (3-Fluorofuran-2-yl)(2-methoxyphenyl)methanol (CAS 1248919-37-0)
- 4-Hydroxy-1,8-naphthyridine-3-carboxylic acid (CAS 342623-43-2)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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