Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate CAS 70384-83-7
| CAS No. | 70384-83-7 |
| Molecular Formula | C12H9ClO4 |
| Molecular Weight | 252.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate.
Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate (CAS 70384-83-7), molecular formula C12H9ClO4 and molecular weight 252.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate (C12H9ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClO4 |
| Molecular Weight | 252.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
Related Ethyl Standards
- 4-Chloro-1-(phenoxymethyl)-1h-pyrazole-3-carboxylic acid (CAS 1006334-27-5)
- 3-((4-Chloro-1h-pyrazol-1-yl)methoxy)benzoic acid (CAS 1006460-39-4)
- 4-[(4-chloro-1h-pyrazol-1-yl)methoxy]benzoic acid (CAS 1006474-24-3)
- 5-chloro-6-cyclopropyl-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1011396-41-0)
- 5-(5-Chloro-2-methoxyphenyl)-1H-pyrazole-3-carboxylic acid (CAS 1037517-30-8)
- Ethyl 2-((5-chloro-2-cyanophenyl)amino)-2-oxoacetate (CAS 1204297-66-4)
- 5-Chloro-1-(2-methoxyphenyl)-1H-pyrazole-3-carboxylic acid (CAS 121562-01-4)
- Methyl 4-Chloro-6-methoxyquinazoline-8-carboxylate (CAS 1240480-28-7)
Recommended Standards
- Ethyl 5-(4-chlorophenyl)-1,3,4-oxadiazole-2-carboxylate (CAS 68496-88-8)
- Ethyl 6-chloro-2-oxo-2H-chromene-3-carboxylate (CAS 70384-80-4)
- Ethyl 5-(4-chlorophenyl)-1,2,4-oxadiazole-3-carboxylate (CAS 40019-35-0)
- Ethyl 6-chloro-3-oxo-3,4-dihydroquinoxaline-2-carboxylate (CAS 4017-32-7)
- 6-Methyl-2-oxoindoline-4-carbonitrile (CAS 2168724-43-2)
- 3-Cyclopropoxy-2-methoxy-4-(methylthio)pyridine (CAS 1243471-50-2)
- 2-Ethoxy-4-formylphenyl cyclohexanecarboxylate (CAS 312525-47-6)
- Abemaciclib Impurity 90 (CAS CATO-C4X-293790)
- 2,4-Dichloro-6-ethoxyquinoline (CAS 1447960-17-9)
- Tert-butyl (5-azaspiro[2.3]Hexan-1-yl)carbamate (CAS 1428547-10-7)
- trans-3-Morpholinocyclobutan-1-amine (CAS 2839511-99-6)
- 3-Methylbutyric acid-1-13C 87994-84-1 Isovaleric acid-1-13C (CAS 87994-84-1)
- 2-(1H-Imidazol-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1310404-67-1)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com