Abemaciclib Impurity 90 CAS CATO-C4X-293790
| CAS No. | CATO-C4X-293790 |
| Molecular Formula | C30H27F4N9 |
| Molecular Weight | 589.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Abemaciclib Impurity 90 (CAS CATO-C4X-293790, C30H27F4N9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Abemaciclib Impurity 90 (C30H27F4N9) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Abemaciclib Impurity 90 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H27F4N9 |
| Molecular Weight | 589.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 9 |
Related Abemaciclib Standards
- Abemaciclib Impurity 179 (CAS CATO-C4X-2937179)
- Abemaciclib impurity 121 (CAS CATO-C4X-2937121)
- Abemaciclib Impurity 58 (CAS CATO-C4X-293758)
- Abemaciclib Impurity 19 (CAS CATO-C4X-293719)
- Abemaciclib Impurity 74 (CAS CATO-C4X-293774)
- Abemaciclib Impurity 150 (CAS CATO-C4X-2937150)
- Abemaciclib Impurity 190 (CAS CATO-C4X-2937190)
- Abemaciclib Impurity 143 (CAS CATO-C4X-2937143)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com