5-Chloro-2-fluoro-4-nitroaniline CAS 704-11-0
| CAS No. | 704-11-0 |
| Molecular Formula | C6H4ClFN2O2 |
| Molecular Weight | 190.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-fluoro-4-nitroaniline is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-2-fluoro-4-nitroaniline (CAS 704-11-0), a certified reference material (molecular formula C6H4ClFN2O2, MW 190.56 g/mol) for analytical method development and quality control.
Based on its molecular formula C6H4ClFN2O2, 5-Chloro-2-fluoro-4-nitroaniline contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 190.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2-fluoro-4-nitroaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4ClFN2O2 |
| Molecular Weight | 190.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-5-fluoro-4-methyl-3-nitropyridine (CAS 1003711-51-0)
- 5-Chloro-4-fluoro-2-nitroaniline (CAS 104222-34-6)
- 3-Chloro-4-fluoro-2-nitroaniline (CAS 1059081-23-0)
- 5-Chloro-3-fluoro-2-nitroaniline (CAS 1352457-23-8)
- 2-Chloro-5-fluoro-4-hydroxybenzoic acid (CAS 1394954-06-3)
- 2-Chloro-4-fluoro-5-nitroaniline (CAS 139626-20-3)
- Methyl 2-Chloro-5-fluoropyrimidine-4-carboxylate (CAS 1404364-32-4)
- 4-Chloro-2-fluoro-6-nitroaniline (CAS 1482558-25-7)
Recommended Standards
- 5-Chloro-2-fluoro-4-hydroxybenzoic acid (CAS 593280-19-4)
- 5-Chloro-3-fluoro-2-hydroxybenzoic acid (CAS 844503-43-1)
- 4-Chloro-5-fluoro-2-nitroaniline (CAS 428871-64-1)
- 6-Chloro-2-fluoro-3-hydroxybenzoic acid (CAS 91659-28-8)
- 2-(3-Nitro-5-(trifluoromethyl)-1H-pyrazol-1-yl)propanoic acid (CAS 1174835-47-2)
- [5-(4-Chlorophenyl)-1,2-oxazol-3-yl]methyl 2,4-dichlorobenzoate (CAS 338777-02-9)
- 4-Chloro-2-methyl-2H-indazole (CAS 162502-54-7)
- N-(5-amino-2-morpholinophenyl)butyramide (CAS 1071288-64-6)
- 2-[3-(2,4-dioxohexahydropyrimidin-1-yl)phenoxy]acetic acid (CAS 2633725-29-6)
- Ethyl (E)-3-bromo-6-(2-(5-chlorothiophen-2-yl)vinyl)-2-hydroxybenzoate (CAS 365542-87-6)
- (1R)-1-(oxetan-3-yl)ethanol (CAS 2375165-27-6)
- Methyl 2-(2-methanesulfonyl-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate (CAS 1315366-44-9)
- 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-ene-1-carbonitrile (CAS 2377299-44-8)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
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