Pentoxifylline Impurity N3 CAS 70486-28-1
| CAS No. | 70486-28-1 |
| Molecular Formula | C12H20N4O2 |
| Molecular Weight | 252.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Pentoxifylline Impurity N3 (C12H20N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Pentoxifylline Impurity N3 (CAS 70486-28-1) is a certified pharmaceutical impurity reference standard with the molecular formula C12H20N4O2 and a molecular weight of 252.31 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pentoxifylline Impurity N3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H20N4O2 |
| Molecular Weight | 252.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 4 |
Related Pentoxifylline Standards
- Pentoxifylline impurity 38 (CAS CATO-C4X-172838)
- Pentoxifylline Impurity 14 (CAS 6493-07-8)
- Pentoxifylline EP Impurity D (CAS 59413-14-8)
- Pentoxifylline EP Impurity I (CAS 55247-90-0)
- Pentoxifylline Impurity 15 (CAS 1246816-64-7)
- Pentoxifylline (CAS 6493-05-6)
- Pentoxifylline EP Impurity G (CAS 93079-86-8)
- Pentoxifylline impurity 35 (CAS CATO-C4X-172835)
Recommended Standards
- Benzo[k]fluoranthene (CAS 207-08-9)
- Benzo[e]pyrene (CAS 192-97-2)
- Benzo(A)Pyrene (CAS 50-32-8)
- Benzo[b]fluoranthene (CAS 205-99-2)
- Vortioxetine Impurity 136 (CAS CATO-C4X-1056136)
- Triamcinolone Acetonide Impurity 42 (CAS CATO-C4X-132642)
- Ropivacaine EP Impurity G HCI (CAS 112773-90-7)
- (1R,2S)-2-([1,1'-biphenyl]-4-yl)cyclopropan-1-amine hydrochloride (CAS 1314324-11-2)
- 3-(1-((4-Bromophenyl)sulfonyl)pyrrolidin-2-yl)-5-((4-(tert-butyl)benzyl)thio)-4-methyl-4H-1,2,4-triazole (CAS 344268-12-8)
- cis-2-Hydroxycyclohexanecarboxamide (CAS 73045-98-4)
- 3-((2,4-Dimethylphenyl)amino)-3-oxopropanoic acid (CAS 58271-38-8)
- Methyl 2,5-dichloro-4-fluorophenylacetate (CAS 1806277-08-6)
- (S)-2-((1-(tert-Butoxycarbonyl)piperidin-3-yl)thio)acetic acid (CAS 1353994-79-2)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com