Benzyl L-leucyl-L-phenylalaninate (TFA) CAS 70637-28-4
| CAS No. | 70637-28-4 |
| Molecular Formula | C22H28N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Benzyl L-leucyl-L-phenylalaninate (TFA).
Benzyl L-leucyl-L-phenylalaninate (TFA) (CAS 70637-28-4) is a high-purity analytical reference standard with the molecular formula C22H28N2O3C2HF3O2 and a molecular weight of 482.50 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Benzyl L-leucyl-L-phenylalaninate (TFA) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 482.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H28N2O3 C2HF3O2 |
| Molecular Weight | 482.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 4-Oxo-4-(tetrahydro-2-furanylmethoxy)butanoic acid (CAS 314767-53-8)
- 3-(2-chlorophenyl)-1,2,4-thiadiazol-5-amine (CAS 19922-06-6)
- DMT-dT Phosphoramidite (CAS 98796-51-1)
- Ethyl (2Z)-2-chloro-2-{2-[4-(propan-2-yl)phenyl]hydrazin-1-ylidene}acetate (CAS 1264088-01-8)
- 5-Isopropyl-3,8-dimethylnaphthalen-2-ol (CAS 2102-75-2)
- Ethyl 2-(2-(methylamino)thiazol-4-yl)acetate (CAS 64986-99-8)
- (R)-2-Amino-2-(3-(trifluoromethoxy)phenyl)acetic acid (CAS 1228569-10-5)
- Ethyl 2-(2-(thiophen-2-yl)-1H-indol-1-yl)acetate (CAS 913527-26-1)
- 3-Chloro-2-ethyl-5-(trifluoromethyl)pyridine (CAS 303147-84-4)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com